Amyloid precursor protein: more than just neurodegeneration

Pex14p, more than just a docking protein.

After binding newly synthesized peroxisomal matrix proteins in the cytosol, the second task of Pex5p, the peroxisomal cycling receptor, is to carry these proteins to the peroxisomal membrane. Defining the nature of the events that occur at this membrane system and which ultimately result in the translocation of the cargo proteins into the matrix of the organelle and in the recycling of Pex5p ba...

Protein aggregation: more than just fibrils.

The aggregation of misfolded proteins into amyloid fibrils, and the importance of this step for various diseases, is well known. However, it is becoming apparent that the fibril is not the only structure that aggregating proteins of widely different types may adopt. Around the isoelectric point, when the net charge is essentially zero, rather monodisperse and quasi-amorphous nanoscale particles...

More than just vanilla.

More than just big ears

To the non-specialist, large ears in elephants used to mean African, small ears, Indian. But to taxonomists African elephants have long posed a more complex puzzle. During the nineteenth century, it was fashionable for wealthy trophy hunters to assign their own names to species they had shot destined for the museums of Europe. At least 18 elephant subspecies were claimed following this fashion....

EHPnet: More Than Just Unleaded